🧠 Clinical Decision Dynamics
- Diverse care contexts
- Multiple specialties
- Representative patient cohorts
- Cross-system comparisons
Human Values Project
The Human Values Project (HVP) is an international research initiative exploring how artificial intelligence systems can align with human values in medical decision-making. Led by Dr. Isaac Kohane at Harvard Medical School, this effort is currently in its foundational phase.
The Clinical Decision Dynamics Study explores how clinicians and advanced artificial-intelligence models weigh complex medical choices—such as deciding which of two patients should be seen first—when time and information are limited. By comparing human experts' triage judgments with those generated by state-of-the-art large language models, we aim to understand where people and AI align, where they diverge, and how decision-making can be safely "tuned" to reflect real-world clinical values.
Key Publications
Published in NEJM, 2024
Published in NEJM, 2024
Get Involved
Participate in this Study
Are you a clinician, nurse practitioner, or other frontline provider?
Answer questions on real-world clinical scenarios and help us align future AI tools with patient values.
Collaborate with Us
We partner with researchers, health systems, and clinical teams who share our goal of value-aligned AI in medicine. Please reach out if you'd like to collaborate with us.
Research Framework
📊 LLM Alignment Benchmarking
- Decision concordance
- Patient-value alignment
- Stability & consistency
- Robustness across settings
📜 Normative Guidance
- Stakeholder co-design
- Value frameworks
- Deployment playbooks
- Continuous evaluation
Research Team
Isaac Kohane, MD, PhD
Payal Chandak, PhD
Raheel Sayeed, MD
